Redox reactions serve as a transduction modality for biological to electrical communication and redox-cycling from interaction of a pair of mediators with the analyte can amplify signals. We further amplify the signal responses of a standard redox capacitor by nanoconfinement of the electrochemical signal measurements.
Biosensing is a rapidly growing line of research in academia and industry. This talk will focus on relevant applications for biosensing technologies for Human State Assessments in DoD, Athletics, Clinical, and General Population applications.
We fabricate and functionalize silicon-nitride microring for detecting attachment of Neuropeptide Y (NPY) molecules, commonly associated with human stress. For 4 µg/ml NPY concentration in aqueous solution we experimentally observe ~0.4 nm resonance shift.
Terahertz spectroscopic gas sensors can detect a range of breath volatiles at part per trillion-level of dilution with absolute specificity. We report on statistical modeling of fatigue based on THz analyses of breath, which can be used in a range of civilian and military applications.
Continuous ultra-weak photon emission without external stimuli or luminphores have been observed in living systems. The intensity of “biophotons” released from this process reflect the physiological state and could serve as an additional mechanism of cellular communication to compliment the established chemical and electrical signaling.