Clinical Electrophysiology -> SVT/AVNRT/WPW/AT: -> Epidemiology of Cardiac Arrhythmias/ Epidemiology D-PO01 - Featured Poster Session (ID 11) Poster

D-PO01-032 - Is Drinking Coffee Associated With An Increased Risk Of Arrhythmia? (ID 888)

 E. Kim: Nothing relevant to disclose.


Background: Despite the popular belief that coffee increases the risk of arrhythmias, the literature has demonstrated inconsistent relationships between coffee and certain arrhythmias.
Objective: We sought to investigate the association between habitual caffeine consumption and the risk of arrhythmia in a large population-based prospective cohort study.
Methods: Among 503,317 participants in UK Biobank, coffee intake information and relevant covariate data were available for 357,022 participants (mean age=56.83±7.98, female 53.5%). We performed multivariate Cox proportional hazards regression analysis to test the association between coffee consumption and arrhythmia risk and plotted Kaplan-Meier curve for cumulative incidence of arrhythmia by coffee intake.
Results: Over 5.25±2.1 years, there were 8,159 incident arrhythmias diagnosed (6,999 atrial fibrillation or atrial flutter, 890 supraventricular tachycardia, 459 ventricular tachycardia, 385 premature ventricular complex). Compared with no consumption, coffee consumption of 1-2, 3-4, 5 or greater cups a day was associated a significantly lower risk of arrhythmia (HR 0.90, p<0.0001; HR 0.86, p<0.0001; HR 0.85 p=0.0005; HR 0.88, P=0.05, respectively, Figure). In Each additional daily cup of coffee was associated with 4% lower incidence of arrhythmia (HR 0.96, CI 0.941-0.98, p<0.0001). A reduction in arrhythmia incidence was observed for each subtype except for premature ventricular complexes, which did not reach statistical significance.
Conclusion: Regular coffee consumption is associated with a significantly lower risk of arrhythmias.