Clinical Electrophysiology -> SCA Risk Assessment: -> Clinical Risk Assessment Techniques D-PO01 - Featured Poster Session (ID 11) Poster

D-PO01-026 - Association Leisure Time Physical Activity With Risk Of Sudden Cardiac Arrest In The General Population: A Nationwide Cohort Study Of The Dose-response Relationship (ID 886)


Background: It is unknown that how much physical activity is required to reduce the risk of sudden cardiac arrest (SCA) and whether high volume of physical activity increase the risk of SCA.
Objective: To quantify the dose response relationship between leisure time physical activity (LTPA) and SCA.
Methods: In the population-based cohort study, 506,805 individuals (mean age, 48±14 years) participated in the Korean National Health Screening Program. On the basis of LTPA energy expenditure per week derived from self reported questionnaire, we evaluated the effect of LTPA at different energy expenditures on the SCA.
Results: During a median follow up of 5 years, the incidence of SCA was 41.1 events per 100,000 person-year. Compared with inactive individuals, those who met the recommended minimum LTPA level (7.5-15.0 metabolic equivalent hours per week) had a 36% lower risk of SCA (HR 0.64; 95% CI 0.53-0.77) and those who reported 2 to 3 times the recommended LTPA had the maximum benefit for reduced risk of SCA (HR 0.58; 95% CI 0.44-0.76). The continued benefits were observed up to 5 times the recommended LTPA. In addition, there was no evidence of increased risk of SCA when more than 5 times the recommended (HR 0.74; 95% CI 0.50-1.09). These associations were consistent regardless of age, sex, BMI, heart failure, prior myocardial infarction and across categories of Framingham cardiovascular disease risk score.
Conclusion: The beneficial effect of LTPA on SCA started at a dose below the recommended minimum LTPA and continued up to 5 times the recommended minimum. No excess risk of SCA among individuals performing 5 or more times the recommended regardless of cardiovascular diseases or lifestyle risk factors.