Allied Professionals (Non-physician submissions only) -> Clinical Research D-PO01 - Featured Poster Session (ID 11) Poster

D-PO01-050 - Left Atrial Volume Constructed By High-resolution Mapping Is A Useful Indicator Of Atrial Fibrillation Recurrence After Pulmonary Vein Isolation (ID 60)

Abstract

Background: Left atrial (LA) enlargement, represented by left atrial volume (LAV), has been reported as a predictor of atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). However, whether LAV constructed by high-resolution mapping using PentaRay catheter (LAV-FAM), a five-branch multipolar catheter, predicts AF recurrence after PVI is rarely evaluated.
Objective: To assess the usefulness of LAV-FAM in addition to left atrial volume measured by echocardiography (LAV-Echo) for predicting AF recurrence after PVI.
Methods: This single center study involved consecutive 119 patients who underwent PVI for AF for the first time by high-resolution mapping system between November 2017 and June 2019 at Juntendo University Hospital, Tokyo, Japan. LAV-FAM was constructed just before PVI by PentaRay catheter during atrial pacing.
Results: The mean value of LAV-FAM in addition to LAV-Echo were 106.8 ± 28.0 mL and 72.3 ± 22.5 mL, respectively. The median and the range of follow up period for AF recurrence were 184 and 90-638 days. AF recurrence occurred in 23 patients (21.7%). LAV-FAM at PVI was significantly larger in AF recurrence patients compared to those without it (118.6 ± 32.9 mL vs. 104.0 ± 26.0 mL, p=0.027) while LAV-Echo in AF recurrence patients was not different. Unadjusted Kaplan-Meier analysis revealed higher cumulative incidence of AF recurrence in patients with highest tertile of LAV-FAM compared to those in lowest tertile of LAVI-FAM (log rank p=0.044, Fig. A) while no differences observed in LAV-Echo.
Conclusion: Findings in this study may suggest LAV-FAM constructed using PentaRay catheter is a useful indicator of AF recurrence compared with LAV-Echo.
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