Catheter Ablation -> Atrial Fibrillation & Atrial Flutter: -> Mapping & Imaging D-PO04 - Poster Session IV (ID 15) Poster

D-PO04-188 - Conduction Velocity Of Left Atrial Electrical Charge Density (ID 489)

  L. Dang: Honoraria/Speaking/Consulting Fee - Acutus Medical Inc. Stock or Stock Options - Non-Public (Including Start-up) - Acutus Medical Inc.


Background: Endocardial conduction velocity (CV, m/s) of cardiac electrical activation has not been assessed globally.
Objective: The CV of the charge density (C/cm) in the entire left atrium (LA) was determined using non-contact charge-density (NCCD) mapping.
Methods: Patients with persistent atrial fibrillation (N=6) and atypical flutter (N=2) underwent NCCD mapping procedure (AcQMap). Sinus rhythm (SR) was recorded pre or post ablation by roving the AcQMap catheter in the LA. NCCD maps were created from time-aligned AcQMap catheter positions according to a time reference. Peak spatiotemporal downstroke of CD was used to compute local activation time (LAT), and CV was computed using a polynomial fitting method. CV was also computed along the coronary sinus (CS) based on the LAT and the distance between the electrodes of a decapolar catheter.
Results: Figure 1 presents the CV and LAT map of the LA in SR. The arrows indicate the direction and magnitude of the CD propagation (blue to red). The CV ranges between 0.01 and 2 m/s. LAT (grayscale) and isochrone are also displayed. In this example, the fastest CV region is located at left atrial appendage, septal-low-posterior LA and anterior LA. The CVs computed along the CS with LAT and distance ranges between 1.2 and 1.5 m/s, which corresponds to the CVs from the NCCD computed from the polynomial fitting method.
Conclusion: This study shows the feasibility to compute CV of the entire LA using a NCCD mapping system (AcQMap) and reveals preferential paths of electrical conduction in the atrium.