Catheter Ablation -> Atrial Fibrillation & Atrial Flutter: -> Clinical Trials / Outcomes D-PO03 - Poster Session III (ID 48) Poster

D-PO03-169 - Incidence And Predictors Of 30-day Acute Cerebrovascular Accidents Post Atrial Fibrillation Catheter Ablation (ID 349)

 A.M. Sridhar: Nothing relevant to disclose.


Background: Catheter ablation for atrial fibrillation (AF) is increasingly being used as first-line therapy for AF
Objective: In this study, we investigate the 30-day incidence and predictors of acute cerebrovascular accidents (CVA) post catheter ablation for AF
Methods: The Nationwide Readmission Database (NRD) from 2010-2015Q3 was queried for admissions with an ablation procedure and a concurrent AF diagnosis. The primary endpoint was a composite endpoint of CVA during index admission and CVA on re-admission in the first 30 days. Logistic regression models were fit to test for associations between the incidence of endpoints and the covariates of interest; which included age, gender, hospital characteristics (size, procedural volume, urban/rural status, teaching status), CHA2DS2-VASc comorbidity score and its components. Appropriate survey weighting methodology was applied to generate nationally representative estimates
Results: Of 67090 weighted hospitalizations for AF ablation, 566 (0.8%) had CVA during index admission or in first 30-days. In multivariable regression analysis, predictors of CVA included HTN (OR 1.39, 95% CI 1.04, 1.85), CHF (OR 4.97, 95% CI 3.32, 7.44), prior Stroke/TIA (OR 3.25, 95% CI 2.39, 4.42) and a lower procedural volume (OR for higher procedural volume: 0.6, 95% CI 0.42, 0.85). CHA2DS2-VASc score (OR 1.27, 95% CI 1.17, 1.39) was associated with CVA in univariate analysis
Conclusion: We found the CVA incidence within 30-days of catheter-based AF ablation therapy to be 0.8%. CHA2DS2-VASc score was associated with CVA. HTN, CHF, prior stroke/TIA, and procedural volume were predictive of CVA