Catheter Ablation -> Atrial Fibrillation & Atrial Flutter: -> Clinical Trials / Outcomes D-PO01 - Featured Poster Session (ID 11) Poster


Background: Atrial Index (AI) is a new lesion quality marker that has been demonstrated to allow acute durable pulmonary vein (PV) isolation followed by a high single-procedure arrhythmia-free survival in single-center studies.
Objective: This prospective, multi-center study was designed to evaluate the reproducibility of PV isolation guided by the AI. Now we report the one-year outcome.
Methods: A total of 490 consecutive patients with paroxysmal (80.4%) and persistent AF underwent first time PV encircling and were divided in four study groups according to operator preference in choosing the ablation catheter (a contact force (ST) or contact force sourround flow (STSF) catheter) and the AI setting (330 at posterior and 450 at anterior wall or 380 at posterior and 500 at anterior wall). Radiofrequency energy was delivered targeting interlesion distance ≤ 6 mm.
Results: At 12 months follow-up a high rate of freedom from AF recurrences was observed in patients with both paroxysmal (91%) and persistent (83.3%, p=0.039) AF. There was no difference in the rate of atrial arrhythmias recurrence among the four study groups (4.5% in Group ST330-450, 12.2% in Group ST 380-500, 14.9% in Group STSF330-450, 9.4% in Group STSF380-500, p=0.083). At 12 months follow-up the rate of atrial arrhythmias recurrence was also similar between patients treated with a ST catheter (8%) and STSF catheter (12.1%, p=0.2) and between patients treated with an AI settings of 330-450 (10.9%) and an AI of 380-500 (10.3%, p=0.64).
Conclusion: An ablation protocol respecting strict criteria for contiguity and quality lesion resulted in high rate of freedom from AF recurrence, both in patients with paroxysmal and persistent AF, irrespective of the ablation catheters, and AI settings chosen by the operator.