Clinical Electrophysiology -> SVT/AVNRT/WPW/AT: -> Epidemiology of Cardiac Arrhythmias/ Epidemiology D-PO04 - Poster Session IV (ID 15) Poster

D-PO04-232 - Lifestyle And New-onset Atrial Fibrillation In Patients With Type 2 Diabetes Mellitus: A Nationwide Population-based Study (ID 1245)


Background: Type 2 Diabetes mellitus (DM) is associated with cardiovascular diseases, including atrial fibrillation (AF) as well as atherosclerotic disease.
Objective: We explored the clinical effects of lifestyle, such as smoking, alcohol consumption, and physical activity, on the development of new-onset AF in patients with DM.
Methods: Using the Korean National Health Insurance Service database, subjects diagnosed with type 2 DM between 2009 and 2012 were screened, and patients with a previous history of AF were excluded. Of 2,551,036 included patients, we investigated the association between smoking, alcohol consumption, physical activity, and new-onset AF.
Results: AF was newly diagnosed in 73,988 patients during the median follow-up period of 7.1 years. Both ex-smokers (hazard ratio [HR] 1.046, 95% confidence interval [CI] 1.023-1.069) and current smokers (HR 1.056, 95% CI 1.033-1.080) showed a higher risk of AF. Subjects with moderate (15-29 g/day) (HR 1.117, 95% CI 1.087-1.149) and heavy (≥30 g/day) (HR 1.244, 95% CI 1.210-1.278) alcohol consumption demonstrated higher risks of AF, while subjects with mild drinking (<15 g/day) showed similar risk (HR 1.012, 95% CI 0.991-1.034) compared to that of non-drinkers. Patients with moderate-to-vigorous physical activity showed a lower risk of AF (HR 0.928, 95% CI 0.914-0.942). In subgroup analyses by sex, significant interaction was observed between smoking and sex, but not among alcohol consumption, physical activity, and sex.
Conclusion: Smoking, alcohol consumption, and physical activity are related to new-onset AF in patients with DM. Lifestyle management would be important to modify the risk of AF in these populations.