Clinical Electrophysiology -> SCA Risk Assessment: -> Signal Processing Techniques (SAECG/TWA, HRV, QT interval) D-PO04 - Poster Session IV (ID 15) Poster

D-PO04-230 - Long-term Prognosis Of Asian Patients With Short Qt Interval (ID 1243)


Background: Short QT syndrome (SQTS) is a rare, inherited heart disease presenting as sudden cardiac death. The characteristics and prognosis of SQTS in Asian patients have not been known.
Objective: The aim of our study was to determine clinical characteristics and outcome of the patients with short QT interval (SQTI) in Asian population.
Methods: We consecutively included patients with short QT interval (SQTI). STQI was defined as corrected QT interval ≤340 ms in serial electrocardiograms. Patients without SQTI and overt cardiovascular disease were included by 1:4 age- and sex-matching. Characteristics of electrocardiogram and cardiovascular events were compared between patients with and without SQTI.
Results: Thirty-four patients [age, 23.5 (21-30.5) years; male, 31] were followed up for 4.8 (2.0-7.8) years. Young (<40 years) male were dominant. Symptoms included palpitation (n=4, 11.8%), loss of consciousness (n=3, 8.8%), and chest pain (n=3, 8.8%). Early repolarization, tall T wave, J wave, and U wave were more frequent in patients with SQTI than the patients without SQTI. QT dispersion [44.0 (28.0-73.0) vs 20.0 (12.0-35.0) ms, p<0.001] was significantly higher and heart rate [52.0 (47.0-58.0) vs 70.0 (62.3-84.0) /min, p<0.001] was significantly slower in patients with SQTI than patients without SQTI. Atrial fibrillation (11.8% vs 2.2%, p=0.030) and ventricular tachyarrhythmia (5.8% vs 0%, p=0.039) were significantly more frequent in patients with SQTI than patients without SQTI. (Table 1)
Conclusion: In Asian patients, SQTI is associated with atrial and ventricular arrhythmias.