Cardiovascular Implantable Electronic Devices -> Bradycardia Devices: -> Indications D-PO03 - Poster Session III (ID 48) Poster

D-PO03-084 - The Correlation Between Duration Of Pseudo-delta Wave And Left Ventricular Mechanical Dyssynchrony In Non-selective His Bundle Pacing (ID 1097)

Abstract

Background: Previous studies have revealed that there were no significant differences between selective His bundle pacing (SHBP) and non-selective His bundle pacing (NSHBP) assessed by hemodynamic status. However, it has not been unclear whether NSHBP is equal to SHBP regarding left ventricular (LV) mechanical dyssynchrony.
Objective: The aim of this study is to assess the correlation between duration of pseudo-delta wave resulting from right ventricular septal activation and LV mechanical dyssynchrony by two-dimensional speckle tracking imaging in NSHBP.
Methods: We studied 16 consecutive patients who received permanent His bundle pacing. Radial strain (RS), circumferential strain (CS) and longitudinal strain (LS) were investigated and time-strain curves were obtained in each 6 segments during NSHBP. We analyzed the maximal difference (Tmax), standard deviation (SD) of time to peak strain, and evaluated the relationship between duration of pseudo-delta wave and echocardiographic parameters.
Results: The duration of pseudo-delta wave was strongly correlated with LS-Tmax (r=0.726, p<0.001), LS-SD (r=0.609, p=0.012), weakly to moderately associated with CS-Tmax (r=0.467, p=0.068) and CS-SD (r=0.326, p=0.218), but not related to RS-Tmax and RS-SD. (Figure)
Conclusion: This study revealed that duration of pseudo-delta wave was especially associated with longitudinal dyssynchrony. Higher degree of right ventricular septal preexcitation might have worse effect on LV dyssynchrony in NSHBP.
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