Catheter Ablation -> Atrial Fibrillation & Atrial Flutter: -> Ablation Techniques D-PO02 - Poster Session II (ID 47) Poster

D-PO02-155 - First In Man Evaluation Of Temperature Guided Ablation (TGA) For Pulmonary Vein Isolation (ID 1035)


Background: Irrigated 3.5-mm radiofrequency (RF) ablation catheters are widely used to perform pulmonary vein isolation (PVI). Temperature guided ablation (TGA) is a novel mode of focal RF ablation allowing higher power delivery in a low-flow setting via a novel radiofrequency (RF) catheter equipped with micro-temperatures sensors and mini-electrodes. With TGA mode high energy up to 50 Watts can be delivered.
Objective: The aim of this ‘first in man’ study was to evaluate the feasibility and safety of TGA in an ablation protocol for pulmonary vein isolation (PVI).
Methods: TGA was evaluated in 11 consecutive patients with atrial fibrillation (AF) that underwent PV encircling. Target power was set at 50 watts at the anterior wall (ablation index, AI 550) and 35W at the posterior wall (AI, 400). The temperature threshold for flow increase was set at 42° and 40° (for the last 7 cases).
Results: TGA resulted in PVI after 54±9 RF applications. Median RF delivery time was 1270±260sec. Median delivered power was 50±2,8Watts at the anterior wall and 35±0Watts at the posterior wall. Incidence of first-pass isolation was 100%. Mean RF irrigation fluid delivery was 207±23ml. No audible steam pop was observed.
Conclusion: TGA seems an efficient ablation mode for PVI. Further studies are needed to evaluate efficacy and safety.